Generating parameters using AMBER's built in General Forcefield (gaff): Difference between revisions

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If system contains residue(s) or ligand(s) which is not parametrized in AMBER libraries and there is no force field parameters for it, you need to calculate them :)
If system contains residue(s) or ligand(s) which is not parametrized in [[AMBER]] libraries and there is no force field parameters for it, you need to calculate them :)


[http://www.rosswalker.co.uk/tutorials/amber_workshop/Tutorial_five/create_prmtop.htm Here] you can find very useful tutorial written by Ross Walker how to create topology and coordinate files for the prescription drug Sustiva.
[http://www.rosswalker.co.uk/tutorials/amber_workshop/Tutorial_five/create_prmtop.htm Here] you can find very useful tutorial written by Ross Walker how to create topology and coordinate files for the drug Sustiva (efavirenz).

Latest revision as of 18:47, 12 May 2008

If system contains residue(s) or ligand(s) which is not parametrized in AMBER libraries and there is no force field parameters for it, you need to calculate them :)

Here you can find very useful tutorial written by Ross Walker how to create topology and coordinate files for the drug Sustiva (efavirenz).